A term child is delivered by spontaneous vaginal delivery with no complications. On physical examination the child has restricted movement in shoulder and elbow joints, bilateral hip dislocations and coarse facial features. Laboratory studies show that the activities of β-hexosaminidase, iduronate sulfatase, and arylsulfatase A are 20 times normal in serum but are deficient in the cultured fibroblasts. This disease is associated with which of the following abnormal cellular components?
A- Apolipoprotein B-48
D- Rough endoplasmic reticulum
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